Social sciences were built from comparison methods assembling field works and data, either quantitative or qualitative. Big Data offers new opportunities to extend this requirement to build commensurable data sets. The paper tells the story of the two previous quantification eras (census and polls) in order to demonstrate the need for a new agency to be considered as the target of this new generation of social sciences: that of objects as ANT proposed and of replications that propagate all over the digital networks. The case study of Latour’s topofil of Boa Vista is revisited to explore how a qualitative method dedicated to comparison and an ANT approach extended in a replication theory may offer new insights from any field study and may use the digital ressources to do so.